為了探討角膜移植術,移植片與接受者鑽取孔尺度之差異對術後中心角膜屈光度的影響,本文回溯性地檢查了69人共74隻接受角膜移植的眼睛(其中台大醫院病例47眼,馬偕醫院27眼),其術後追蹤至少12個月以上,測量其術後之角膜屈光度。依手術中移植片比接受者鑽取孔尺度差異的程度分成二組,第一組為相差0.5mm,第二組為相差0.3mm以下。結果術後平均角膜屈光度第一組為45.3±3.3D(n=58),第二組為42.7±4.6D(n=16);術後角膜散光分別為4.26±2.55D,4.48±3.90D;二項均無統計上的差異。同時在相同程度的移植片尺度差異下,於不同大小的接受者角膜鑽孔,術後角膜屈光度也沒有差異。需要更多病例的前瞻性研究,以提高角膜移植合併水晶體手術中術後屈光球鏡當量的穩定性。
To study the effect of the graft-host disparity on the central corneal curvature afer penetrating keratoplasty, we retrospectively examined 74 eyes among 69 patients receiving penetrating keratoplasty, who had been followed-up for at least 12 months. The subjects were divided into two groups according to the graft-host disparity during operation, the first group (A) 0.5mm and the second group (B) not more than 0.3mm. The resultant keratometric readings were 45.3±3.3D (n=58) in group A, and 42.7±4.6D (n=16) in group B; the keratometric astigmatism were 4.26±2.55D and 4.48±3.90D respectively. No statistic difference was found in either items. With the same graft-host disparity, there was no statistical difference of postoperative corneal curvature among recipients with diffenent punch sizes. We suggest further studies with more cases to set up the post-operative keratometrical data for eash surgeon to improve the predictability of the spherical equivalent after penetrating keratoplasty combined with lens surgery.