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Wegener氏肉芽腫併鞏膜炎－病例報告
Wegener's Granulomatosis with Scleritis-A Case Report
摘要
Wegener氏肉芽腫(Wegener's granulomatosis)是一少見的全身性疾病，影響眼部的機率很高。在此，我們報告一病例，病人為27歲男性，修車工人，主要症狀是乾咳及咳血，胸部X光的表現是兩側上肺部開洞性的病灶(cavitary lesions)。眼部的表現主要是鞏膜炎及周邊潰瘍性角膜炎(peripheral ulcerative keratitis)，Wegener氏肉芽腫的診斷乃是經向開胸手術肺部活體組織檢查(open lung biopsy)。在此將探討其眼部症狀的表現，以及眼科醫師在Wegener氏肉芽腫的早期診斷上所能扮演的角色。
關鍵字
無資料並列摘要
Wegener's granulomatosis is a rare systemic disease. The ocular involvement is common. We report the case of a 27-year-old male patient, presenting with dry cough and hemoptysis. Chest xrays revealed bilateral cavitary lung lesions. The definitive diagnosis of Wegener's granulomatosis was made via open lung biopsy. The patient's right eye showed peripheral ulcerative keratitis and necrotizing scleritis and the left eye revealed scleritis. After topical and systemic treatment of steroids, the ocular inflammation became subsided. The systemic manifestations were cured by oral cytotoxic agents (cyclophosphamide). After one and a half years of follow up, both eyes were quiet without inflammatory signs. The refractive changes due to thinning of peripheral cornea and blue sclerae of both eyes were noted.
延伸閱讀
- 林肇穗、蘇茂昌、李清課、陳宗琨、郭恆甫、張昭明（1997）。Wegener氏肉芽腫－病例報告。中華民國耳鼻喉科醫學會雜誌，32(4)，439-443。https://doi.org/10.6286/1997.32.4.439
- 張巍耀、許振益（1997）。Wegner氏肉芽腫症。中華民國耳鼻喉科醫學會雜誌，32(5)，355-363。https://doi.org/10.6286/1997.32.5.355
- Kung, L. Y., & Hsiao, H. T. (1998). 嗜伊紅性肉芽腫－病例報告. 中華民國重建整形外科醫學會雜誌, 7(1), 68-72. https://doi.org/10.7096/JPRSA.199803.0014
- 謝捷、吳俊昇、趙勝基、吳志翹、黃雯莉、石擎天（1993）。韋氏肉芽腫病－病例報告。中華民國眼科醫學會雜誌，32(2)，265-269。https://doi.org/10.30048/ACTASOS.199306.0022
- Nishiuma, T., Ohnishi, H., Yoshimura, S., Kinami, S., & Sakamoto, S. (2013). A Case of Granulomatosis with Polyangiitis (Wegener's Granulomatosis) Presenting with Marked Inflamed Tracheobronchial Mucosa. Case Reports in Medicine, 2013(), 125-129-030. https://doi.org/10.1155/2013/208194