硬式透氣隱形眼鏡的配戴對於角膜內皮細胞的影響

The Effects of Rigid Gas Permeable Contact Lens Wear on the Corneal Endothelium

劉斌弘(Ping-Hung Liu) ； 蔡明琪(Ming-Chi Tsai) ； 林昌平(Chang-Ping Lin)

《中華民國眼科醫學會雜誌》 36卷1期 (1997/03) Pp. 31-35

https://doi.org/10.30048/ACTASOS.199703.0006

摘要

本研究共收集了20個配戴RGP隱形眼鏡滿3年的病人，他們之前都未曾使用過其他形式的隱形眼鏡，利用Specular microscope進行角膜內皮細胞的攝影，然後針對其內皮細胞密度(cell density)，六角形細胞出現率(frequency of hexagonality)及細胞大小的變化(polymegethism)，來比較RGP配戴滿2年時及配戴滿3年時與未配戴RGP隱形眼鏡的對照組之間的差異。ANOVA統計的結果顯示，無論是在細胞密度，六角形細胞出現率，或是細胞大小的差異性方面都沒有顯著的差異。

並列摘要

The purpose of this study is to determine the effects of rigid gas permeable (RGP) contact lens wear on the corneal endothelium. We performed specular microscopy on the corneal endothelium of 20 young RGP contact lens wearers at the time of two and three years duration respectively and 13 age-matched non-lens-wearing controls. The parameter, including cell density, mean cell area, standard deviation, coefficient of variation of cell size (CV), maximum cell, minimum cell and hexagonality were displayed. The cell density and mean cell area showed no significant difference (P＞.05) between the data of two and three years duration of wearer and controls. The coefficient of variaiton of cell size (CV) and the frequency of hexagonality also showed no significant change (P＞.05). Our results suggest that the shortterm RGP contact lens wearing does not result in cell density and morphologic change. The long-term effect still need further observation and evaluation.

並列關鍵字

Rigid-Gas-Permeable RGP contact lens ； corneal endothelial cell density ； Pleomorphism ； Polymegethism ； Hexagonality