Retinal Pigment Epithelial Hamartoma-A Case Report

視網膜色素層缺陷瘤－病例報告

黃曼菁(Man-Ching Huang) ； 吳愛卿(Ai-Ching Wu)

《中華民國眼科醫學會雜誌》 38卷2期 (1999/06) Pp. 257-261

https://doi.org/10.30048/ACTASOS.199906.0008

摘要

視網膜色素層缺陷瘤是很罕見的眼底病變，它們是病變處正常所該有之成熟細胞及組識之過度增生。雖然它們很稀竹，但因易被誤認為脈絡膜黑色素瘤或網膜母細胞瘤，所以臨床辨認此一良性腫瘤是十分重要的。我們報告一位六十二歲婦女，她在一九九一年二月七日接受第一次檢查，在左眼眼底我們發現一個稍微突起之棕灰色腫瘤遮蓋部分的視神經盤。此腫瘤上之血管明顯地扭曲，眼底螢光攝影顯示黃斑部之背景脈絡膜螢光被阻擋，並且網膜血管扭曲，晚期螢光滲漏至腫瘤。此病人我們持續追踪六年，眼底病變並無改變。根據其典型之臨床表現及病程，我們認為視網膜色素屬缺陷瘤為其正確診斷，雖然我們無法得到病理之證據。

並列摘要

Hamartomas are benign overgrowths of mature cells and tissues which exist normally in the affected area or part. Harmatoma of RPE are rare fundus lesions, but careful to identify them is important because they may be mistaken for choroid melanoma or retinoblastoma. We report a 62-year-old woman who was first examined on 7 February 1991. A slightly elevated gray-brown gliotic mass obscured the left optic disc. The retinal vasculature in the area of the mass was markedly tortuous. Fluorescin angiography of the left eye showed blockage of background choroidal fluorescein in the lesion area, and demonstrated the retinal vasculature tortuosity, with late leakage into the tumor mass. The patient was followed periodically over next 6 years, and the appearance of the juxtapapillary lesion did not change. According to its typical clinical presentation and course, we believe that RPE hamartoma is the proper diagnosis although the pathological proof is impossible to be achieved.

並列關鍵字

hamartoma ； RPE ； benign tumor