摘要
目的：本篇報告一眼內淋巴瘤之病例，並回顧文獻上之報告。 方法：以眼底攝影紀錄病情變化，並以玻璃體切除術取得標本，進行病理細胞學檢查及flow cytometry。 結果：69歲女性，主訴雙眼視力模糊併暈眩、頭痛，眼底檢查發現兩眼玻璃體混濁，視網膜有數塊黃白色病灶，經左眼玻璃體切除手術，抽出物進行病理細胞學檢查及flow cytometry，結果為惡性大細胞淋巴瘤，且來自B-cell，初期腦部影像檢查、脊髓切片及脊髓液檢查約為陰性。綜合臨床及檢驗結果，診斷為眼內淋巴瘤“經眼部放射治療後，眼底病灶漸行消退，但於治療6個月後發現腦部病灶，因此給予化學治療，但3個月後病人因肺炎併香敗血症過世。 結論：眼內淋巴瘤是一種罕見卻致命的疾病，本篇提出一疑似原發性眼內淋巴瘤之病例，並探討其臨床表現、診斷方式及治療方法。
關鍵字
無資料並列摘要
A 69 year-old female complained of blurred vision, dizziness, headache and unstable gait for many months. Eye examination showed decrease visual acuity, mild anterior segment inflammation, vitreous cells and subretinal yellow infiltrates. Diagnostic vitrectomy was performed and the specimen was immediately sent to pathology laboratory and flow cytometry for analysis. The results revealed malignant large B-cell lymphoma. Neurologic work up was done initially, including cytopathologic exam of CSF and neurologic imaging of brain, but all were negative. According to the clinical and laboratory findings, we made the diagnosis intraocular large B-cell lymphoma. After radiation therapy of eyes, the retinal lesions regressed gradually. However, brain lesions were noted on MRI six months later. Systemic chemotherapy was given and the patient died from the complication of chemotherapy finally.
延伸閱讀
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