Breakdown of the Blood-Aqueous Barrier Caused by Argon Laser Panretinal Photocoagulation in the Rabbit Retina

兔子視網膜汎視網膜光凝固作用對血液前房水柵的影響

陳慕師(Muh-Shy Chen) ； 張慶忠(Ching-Chung Chang) ； 林思源(Szu-Yuan Lin) ； 王鵬程(Peng-Chen Wang) ； 侯平康(Ping-Kang Hou)

《中華民國眼科醫學會雜誌》 45卷4期 (2006/12) Pp. 376-382

https://doi.org/10.30048/ACTASOS.200612.0004

摘要

目的：利用前房蛋白質細胞測量儀分析於兔子視網膜做汎視網膜光凝固作用後，對於血液前房水柵功能的影響。
方法：對10隻有色兔子使用氬雷射做汎視網膜光凝固作用，其條件包括時間為0.1秒，大小為200微米，能量為120毫瓦特，一眼做400個雷射斑。前房蛋白質檢查於雷射作用前和作用後第1，2，3，7，14，28，42，和56天做測量。
結果：雷射光凝固作用後於7天之內呈現明顯的血液前房水柵功能異常，前房蛋白質濃度增加於第1天最明顯，在第7天之內逐漸下降，而在第14天恢復正常。結論：雷射汎視網膜光凝固作用可造成血液前房水柵功能的異常。

並列摘要

Purpose: To evaluate the blood-aqueous barrier function after argon laser panretinal photocoagulation on the normal rabbit retina using laser flare photometry.
Methods: Ten Rex pigmented rabbits were selected and treated with scatter photocoagulation in the nonvascularized retina (400 lesions per eye, 0.1 second exposure, 200 μm spots, 120 mW power setting). Aqueous flare values were measured 1, 2, 3, 7, 14, 28, 42, and 56 days after treatment.
Results: Significant disruption of the blood-aqueous barrier was seen 1 week after photocoagulation. The peak flare intensity value of the treated eyes occurred on day 1, gradually decreased during the first week, and became insignificant by day 14.
Conclusion: The present results have indicated that the argon laser panretinal photocoagulation can produce a breakdown of the blood-aqueous barrier.

並列關鍵字

blood-aqueous barrier ； argon laser panretinal photocoagulation