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The Iolmaster Biometry of Preschool Children with Retinopathy of Prematurity

有早產兒視網膜病變病史之學齡前兒童以IOLMaster測量之結果

摘要


Purpose: To evaluate the refractive and biometric values of preschool children with retinopathy of prematurity (ROP). Methods: We collected data of the right eye of 56 preschool children from 3 to 5 years of age at Far Eastern Memorial Hospital, Taipei, Taiwan. Cycloplegic refractions were measured by automated refractometer, and biometric data were measured by the IOLMaster (Carl Zeiss Meditec AG, Jena, Germany). The Haigis formula was employed to predict lens power. Patients with ROP were categorized as Group 1 (28 eyes), and those with full-term history as Group 2 (28 eyes). Group 1 was further divided into Group 1A (14 eyes), severe ROP treated by laser ablation; and Group 1B (14 eyes), spontaneous regression of ROP without intervention. Refractive and biometric data were compared between groups and subgroups by using nonparametric Wilcoxon rank-sum test. Results: There were insignificant difference in axial length and age between groups and subgroups (p > 0.05). Group 1 had more myopic refractive errors, shallower anterior chamber depth, steeper corneal curvature, and higher lens power compared with Group 2 (p < 0.05). More myopic change and exaggerated biometric findings were found in Group 1A than in Group 1B (p < 0.05). Conclusion: Myopia in preschool children with ROP was not axial myopia, which was attributed to steeper cornea, shallower anterior chamber, and higher lens power. Myopia and abnormal biometric results were more exaggerated in eyes with laser-treated ROP than in those with spontaneously regressed ROP.

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並列摘要


Purpose: To evaluate the refractive and biometric values of preschool children with retinopathy of prematurity (ROP). Methods: We collected data of the right eye of 56 preschool children from 3 to 5 years of age at Far Eastern Memorial Hospital, Taipei, Taiwan. Cycloplegic refractions were measured by automated refractometer, and biometric data were measured by the IOLMaster (Carl Zeiss Meditec AG, Jena, Germany). The Haigis formula was employed to predict lens power. Patients with ROP were categorized as Group 1 (28 eyes), and those with full-term history as Group 2 (28 eyes). Group 1 was further divided into Group 1A (14 eyes), severe ROP treated by laser ablation; and Group 1B (14 eyes), spontaneous regression of ROP without intervention. Refractive and biometric data were compared between groups and subgroups by using nonparametric Wilcoxon rank-sum test. Results: There were insignificant difference in axial length and age between groups and subgroups (p > 0.05). Group 1 had more myopic refractive errors, shallower anterior chamber depth, steeper corneal curvature, and higher lens power compared with Group 2 (p < 0.05). More myopic change and exaggerated biometric findings were found in Group 1A than in Group 1B (p < 0.05). Conclusion: Myopia in preschool children with ROP was not axial myopia, which was attributed to steeper cornea, shallower anterior chamber, and higher lens power. Myopia and abnormal biometric results were more exaggerated in eyes with laser-treated ROP than in those with spontaneously regressed ROP.

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