正子斷層掃描偵測到的大腸腺瘤/大腸癌

Colonic Adenoma/Adenocarcinoma Detected by Positron Emission Tomography

陳遠光(Yen-Kung Chen) ； 蘇章松(Jang-Song Su) ； 廖健發(Alfred C. Liao) ； 柴發順(Fa-Shun Tsai) ； 沈業有(Yeh-You Shen)

《核子醫學雜誌》 14卷3期 (2001/09) Pp. 187-190

https://doi.org/10.6332/ANMS.1403.016

摘要

一位70歲無症狀男性，以氟-18去氧葡萄糖（18F-FDG）進行全身正子斷層掃描，發現，有高代謝性病變於乙狀結腸區。之後，進行大腸鏡檢查，顯示有一息肉距離肛門25公分，穿刺切片病理診斷為管絨毛狀腺瘤（villotubular adenoma），然此息肉外科仍疑為惡性，經手術切除後發現，有一3.5 x 2.4 x 1.5公分的覃狀腫瘤位於乙狀結腸，病理診斷為腺癌併絨毛狀腺瘤。此一發現，顯示正子斷層掃描偵測到的腺瘤可能有惡性變化，由於腺瘤被認為是有可能轉變成惡性，因此正子斷層掃描極有價值用來偵測腺瘤轉變成腺癌。

關鍵字

大腸腺瘤 ； 大腸癌 ； 正子斷層掃描

並列摘要

A 70-year-old asymptomatic man, who underwent whole-body positron emission tomography (PET) with 18F-fluorodeoxyglucose, was found to have a lesion in the sigmoid colon region. Furthermore, colonscopy examination revealed a polyp in a distance 25 cm to anus. Biopsy of the polyp was performed and histopathological study showed to be villotubular adenoma. However, the possibility of malignancy can't be ruled out. A low anterior resection for rectosigmoid colon was then performed and a 3.5×2.4×1.5 cm mass was found. Histopathological study showed an adenocarcinoma with villotubular adenoma. The findings in this case suggest that colonic adenoma detected by PET may accompany with malignant change. Colonic adenomas are considered to have potential for malignant transformation. Therefore, it is noteworthy that PET can be used in the detection of adenoma with malignant change.

並列關鍵字

colonic adenoma ； colon adenocarcinoma ； positron emission tomography