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Acute Abdomen Due to Unusual Metastatic Manifestation of Pulmonary Squamous Cell Carcinoma: A Case Report and Literature Review

急性腹痛:扁平細胞肺癌之罕見的臨床表現-病例報告與文獻回顧

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摘要


由於原發性肺癌轉移,造成急性腹部併發症,且合併非常高的手術死亡率,在先前的文獻已有零星的報告。最近,我們發現一個原發性肺癌的病人,併發致命的小腸轉移及穿孔。 我們回顧文獻,從1961年迄今,原發性肺癌合併小腸轉移且破裂者,共有24個病例。所有病患存活不超過16週,主要的腫瘤細胞型態為扁平細胞癌(11/24,46%),主要的小腸破裂部位是在空腸(16/24,67%)。 肺癌轉移到小腸,其臨床表現以小腸破裂為主且是一個不良預後的警訊。

並列摘要


Acute abdomen due to metastatic primary lung cancer has been reported rarely in the literature, and is associated with a very high operative mortality. Recently, we experienced a patient who presented with a life-threatening complication of small bowel perforation due to the metastasis of primary lung cancer. We reviewed the literature and found that there had been twenty-four cases of lung cancer with small bowel metastasis and perforation since 1961. All patients survived less than 16 weeks and the predominant tumor cell type was squamous cell carcinoma (11/24, 46%). The major site of small bowel perforation was the jejunum (16/24, 67%). In conclusion, lung cancer with metastasis to the small bowel often presents as intestinal perforation and indicates a poor prognosis.

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