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Amniotic Fluid Embolism: A Case Report and Review of the Literature

羊水栓塞:一病例報告及文獻回顧

摘要


羊水栓塞是一少見且非常危急的產科疾病,它含括了多個重要系統且有高死亡率。我們報告一位三十五歲的婦女,在產後兩個小時併發嚴重喘促。此後,迅速發展成心肺停止。胸部X光片表現在右側肺門的浸潤和左側肺野心後肺泡樣斑塊;實驗室檢查表現擴散性血管內凝集病變的特徵。從臨床表現和中央靜脈血的組織發現有胎毛及胎兒扁平細胞,證實羊水栓塞的診斷。在急救及支持性照顧後,病人成功的存活,但因到達前的缺氧性腦病變仍依賴呼吸器支持。

關鍵字

羊水栓塞 心肺停止

並列摘要


Amniotic fluid embolism (AFE) is a rare and very critical obstetrical disease, which involves multiple vital systems and has a high mortality rate. We report a 35-year-old woman complicated with severe dyspnea two hours post-delivery. Cardiopulmonary arrest developed rapidly thereafter. The chest radiography showed a right perihilar infiltration and a retrocardiac alveolar patch in the left lower lung field. The laboratory examination characterized disseminated intravascular coagulopathy. The clinical manifestations and histological findings of lanugo and fetal squamous cells in the central venous blood sample confirmed the diagnosis of amniotic fluid embolism. After emergency resuscitation and supportive care, the patient survived, but still depended on ventilator support due to hypoxic encephalopathy which had occurred before arrival.

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