Desmoplastic Malignant Mediastinal Mesothelioma Presenting as Superior Vena Cava Syndrome: A Case Report and Literature Review

纖維惡性縱膈腔間皮癌以上腔靜脈症候群為臨床表現：病例報告及文獻回顧

劉嘉美(Kah-Mee Law) ； 魏裕峰(Yu-Feng Wei) ； 吳俊廷(Jiun-Ting Wu)

《胸腔醫學》 30卷2期 (2015/04) Pp. 92-98

摘要

惡性縱膈腔間皮瘤是一種很稀少的間皮瘤，大約佔了所有間皮瘤的5%以下，而心包膜間皮瘤是屬於更稀少的間皮瘤。根據一項驗屍解剖個案統計，在500,000個案裡面，其發生率小於0.0022%。我們報告的病例是一位48歲男性病患，第一次出現在門診的主訴是咳嗽合併白色痰液及體重減輕已有2個月的時間。胸腔電腦斷層之下表現為右側獨立性縱隔腔腫瘤，且侵犯到上腔靜脈以及氣管。病理報告顯示為纖維性間皮瘤，並從影像學上判斷應是從心包膜長出來的間皮瘤。這病人在進行化學治療後5天因敗血症病逝。

關鍵字

纖維性 ； 惡性縱膈腔間皮瘤 ； 上腔靜脈症候群

並列摘要

Mediastinal mesothelioma is rare, accounting for less than 5% of all cases of mesothelioma. Primary pericardiac mesothelioma is also a rare type of mesothelioma, with a reported incidence of less than 0.0022% among 500,000 cases in a large necropsy study. Herein, we report the case of a 48-year-old man who presented to our outpatient department due to progressive cough with prominent body weight loss within 2 months. Chest computed tomography showed a right mediastinal mass encasing the superior vena cava with obliterated vessels. The pathology of the mass revealed desmoplastic mesothelioma, which was most likely pericardial in origin, based on the imaging findings. Echocardiography showed tumor thrombus in the superior vena cava, extending to the right atrium. The patient died of sepsis after chemotherapy 5 days later.

並列關鍵字

desmoplastic ； malignant mediastinal mesothelioma ； superior vena cava syndrome