- 期刊
A Rare Pulmonary Metastatic Disease - Low-Grade Endometrial Stromal Sarcoma: A Case Report and Literature Review
一個罕見的轉移性肺腫瘤－低度子宮內膜基質肉瘤：病例報告與文獻回顧
摘要
Pulmonary metastasis of low-grade endometrial stromal sarcoma (ESS) is uncommon. A 36-year-old woman visited our hospital due to right-side pleuritic pain, chest tightness, shortness of breath and non-productive cough for 1 month. Computed tomography showed an ill-defined heterogeneous consolidated lesion in the right lower lobe. The patient had undergone a myomectomy due to uterine myoma 8 years before this visit. To obtain a definitive diagnosis of the lung lesion, we performed wedge resection using video-assisted thoracic surgery (VATS). The initial pathologic diagnosis was sarcoma, grade 3, but this was revised to pulmonary metastasis of low-grade ESS after a genetic study. Medroxyprogesterone acetate was administered as postoperative treatment, but recurrence was detected 24 months after the wedge resection. The patient then underwent VATS for removal of the recurrent pulmonary nodules, followed with laparoscopy-assisted vaginal hysterectomy and bilateral salpingo-oophorectomy. The pathological report was low-grade ESS of the uterus.
並列摘要
子宮內膜基質肉瘤是罕見的轉移性肺腫瘤，我們的案例報告是一個36 歲女性，入院8 年前曾經接受過子宮肌瘤切除，入院前1 個月開始出現右側胸痛、胸悶及咳嗽症狀。胸部電腦斷層發現右下肺葉有實質化病灶合併肋膜積液。經胸腔內視鏡(VATS) 右肺葉的楔形切除術後，初步病理報告為第三度肉瘤，但之後經過基因分析後更正病理報告為低度子宮內膜基質肉瘤合併肺轉移。在病人接受術後Medroxyprogesterone acetate 治療24 個月後發現肺部復發，於是再度接受胸腔內視鏡輔助腫瘤切除，隨後接受腹腔鏡輔助經陰道子宮切除術及雙側輸卵管卵巢切除術確診為低度子宮內膜基質肉瘤。
延伸閱讀
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