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Recurrent Pigmented Villonodular Synovitis of Knee Treated with Surgery and Adjuvant Radiotherapy: A Case Report

手術及輔助性放射治療用於膝關節復發色素絨毛結節狀滑膜炎之治療: 病例報告

摘要


色素絨毛結節狀滑膜炎為一稀有疾病,主要影響關節滑膜並產生類似關節炎的症狀。瀰漫性色素絨毛結節狀滑膜炎在接受手術治療之後,復發的情況並不少見。我們報告一位在初次滑膜切除術後一年又十個月復發的男性病患。他在第二次手術後39天開始接受術後的放射線治療,總劑量為34.5 Gy,以15次分次照射給予。放射治療緩解了疾病相關的症狀,但追蹤的核磁共振影像仍有疾病存在的證據。放射治療對某些瀰漫性色素絨毛結節狀滑膜炎病人可能會有治療上的益處。

並列摘要


Pigmented villonodular synovitis (PVS) is a rare disease involving the synovial membrane and causing symptoms similar to arthritis. In diffuse PVS, recurrence is not uncommon after surgery. We report a male patient with PVS of the knee that recurred 1 year and 10 months after initial synovectomy. He was again operated on and then given adjuvant radiation therapy (RT) with a total dose of 34.5 Gy in 15 fractions beginning 39 days postoperatively. RT relieved his symptoms even though an MRI revealed persistent disease. RT may be beneficial for selected patients with diffuse PVS.

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