防曬劑之接觸過敏：21年臨床經驗

背景：以往的研究認為防曬劑引起皮膚過敏的發生率很低，然而截至目前為止，尚未有針對華人族群之防曬劑過敏的發生率研究。目的：探討以華人族群為基礎之開發中國家的防曬劑過敏發生率。方法：自1980年至2000年，在我們的接觸性皮膚炎特別門診中共有3135位病人接受貼膚試驗，其中有922位男性、2213位女性，若有懷疑對防曬劑光過敏的患者，則進行光貼膚試驗，我們同時也回顧病患的病歷紀錄。結果：共有94名患者在臨床上懷疑是對防曬劑過敏或光過敏，其中真正以貼膚試驗證明有過敏的有17人（18.1％）（2名男性、15名女性），這17人中光過敏的人數有8人（47.1％），在1991年之後，臨床上由於懷疑使用防曬劑不耐而來就診的人數顯著增加，然而實際上真正對防曬劑過敏或光過敏的人數並未增加。結論：由我們的研究發現，台灣人使用防曬劑後出現不適者，真正是接觸性過敏的發生率約18.1％。在一個開發中國家，隨著經濟水平的提升與防曬劑使用的增加，並不會造成防曬劑過敏或光過敏的比例增加。（中華皮誌21：344-352, 2003）

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並列摘要

Background: The incidence of sunscreen (photo) allergy is thought to be low in previous reports, but there is no large-scale, long-term study that documents its incidence in a Chinese-based po9pulation. Objective: To investigate the incidence of sunscreen (photo) allergy in a developing country with a Chinese-based population. Methods: From 1980-2000, a total of 3135 (922 men, 2213 women) patients were patch-tested at our Contact Dermatitis Clinic. Cases of suspected (photo) allergic to sunscreens were enrolled and (photo) patch tested. We also retrospectively reviewed their complete records. Results: Among them, 94 patients were suspected (photo) allergic to sunscreens and were (photo) patch tested. Seventeen of the 94 patients (18.1%)(2 men, 15 women) demonstrated (photo) allergic to the sunscreens. Among them, 8(47.1%) were photoallergic. The number of patients with suspected sunscreen intolerance was increased significantly after the year 1991. However, this did not lead to increment in incidence of sunscreen (photo) sensitivity. Conclusion: The rate of sunscreen (photo) allergy in Taiwan is 18.1% among the sunscreen intolerance patients. Our data may suggest that increased sunscreen usage in a developing country would not lead to increased rate of sunscreen (photo) sensitivity.(Dermatol Sinica 21 : 344-352,2003)

並列關鍵字

Patch test ； Photopatch test ； UV absorbers

國際替代計量

防曬劑之接觸過敏：21年臨床經驗

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