This is a case of a 45-year-old woman who suffered from chronic periodontitis. She had generalized mild gingival inflammation, but her periodontal pocket depth ranged from 5-10mm. The phase I therapy including OHI、SC/RP、endodontic therapy on #17. After evaluation of phase I therapy, UR、UL、LR、LL were treated surgically. The surgical therapy including flap surgery alone on LL, guided tissue regeneration, using Biomend on UR Atrisorb on UL、LR, combined demineralized freeze-dried bone allograft. However, the surgical therapy on UR was done 7 months after RCT on #17. In conclusion, after the treatment, the pocket depth reduced about 3-7mm, the attachment gain around 2-6mm. Also, the infrabony defects were improved radiographically. The oral hygiene of this patient is very good, which might have a very positive impact on the result.