The Relationship between Periodontitis and Preterm birth-A Review

牙周病與早產的關聯性－文獻回顧

何念恩(Nan-En Ho) ； 呂炫堃(Hsein-Kun Lu)

《臺灣牙周病醫學會雜誌》 14卷2期 (2009/06) Pp. 138-153

摘要

牙周病是一種口腔的慢性感染疾病，且近來發現牙周病可能爲早產的危險因子，因此在牙周病和早產的關聯上，有許多的注意力投注於其上。早產及體重過輕是全球性在生產前後發生問題的主因，且這兩者的發生率在現今仍然極高。本篇文獻即探討牙周病能造成早產的假說，並回顧相關的流行病學研究。不論從流行病學的研究、微生物及免疫上的發現，都指出牙周病可能爲早產的重要危險因子。在不同種族間以一致的設計方法做更大型的研究可爲日後的方向。而維持良好的口腔衛生並接受適當的牙周治療是必需的。

關鍵字

牙周炎 ； 早產 ； 體重過輕

並列摘要

Since periodontitis is a chronic oral infection which recently recognized as a potential risk factor for preterm birth, the interests to find the relationship between periodontal disease and adverse pregnant outcomes are raised. Preterm birth and low birth weight are world-wide leading perinatal problems, and their incidence rates are still high even in recent days. The present review focuses on the hypothesis how periodontitis can cause preterm birth, and to review the epidemiological studies including interventional studies, case-control studies, cohort studies, and systematic reviews. Either from the epidemiological studies, the microbiology, or the immunology findings, all suggested that periodontitis might be an important risk factor to preterm birth. Larger studies in different races with uniformed research design are recommended. Maintenance of good oral hygiene and adequate periodontal treatments are advised.

並列關鍵字

periodontitis ； preterm birth ； low birth weight