- 期刊
長期口服雙磷酸鹽類藥物之患者拔牙後傷口癒合不全－病例報告
Incomplete Extraction Wound Healing with Oral Use of Bisphosphonates: A Case Report
摘要
近來有許多報告指出顎骨壞死與使用雙磷酸鹽類藥物可能有關，其中因爲長期口服雙磷酸鹽類藥物引起顎骨骨質壞死的病例有漸漸增加的趨勢，尤其全譽界人口使用口服雙磷酸鹽類藥物治療骨質疏鬆症的比例逐年上升，學者們紛紛發出預警，提醒牙醫師在施行口腔外科手術時必須了解患者的系統性疾病與相關之用藥情況，以避免或是預防此不良併發症的發生。本文報告一位長期服用雙磷酸鹽類藥物治療骨質疏鬆症之82歲女性患者拔牙後傷口癒合情況，除了初期有嚴重的不適感並密集的回診治療以外，於拔牙一個月後至一年中之每三個月定期追蹤顯示，不論是軟組織外觀或是X光攝影之檢查，均顯示該患者之拔牙傷口癒合較一般遲緩而不完全。藉由此報告，希望能提供預防、分辨，甚至是處理服用此類藥物引起之顎骨骨質壞死所應具備的知識與能力。
並列摘要
There have been recent reports in the literature of a possible association between avascular necrosis of the jaws and the use of bisphosphonates. In the present study, we reported a case of incomplete wound healing and jawbone necrosis in the period of one year post extraction in a patient who is undergone with oral bisphosphonate therapy for osteoporosis. Since there have been few similar cases reported in Taiwan, efforts should be made to understand the issue concerned worldwide and to remind dentists there may be a related risk factor for osteonecrosis in the jaws.
延伸閱讀
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