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Lye Corrosion Carcinoma of the Esophagus: A Report of Two Cases

腐蝕性食道炎與食道上皮細胞癌:二病例報告

摘要


腐蝕性食道炎之患者比常人易罹患食道癌,一般潛伏期可長達三、四十年,但是其預後卻比一般食道癌為佳,可能因為腐蝕劑傷害所致之結痂組織可防止癌細胞早期擴散。我們報告兩例曾服食鹼性腐蝕劑而發生食道上皮細胞癌的病患,這兩人也都合併有肺炎及膿胸之併發症。而且病例1從服食鹼液到末期食道癌僅三年半,遠短於一般文獻報導之潛伏期。

並列摘要


Patients with lye corrosive injury had a higher risk of developing esophageal carcinoma than the general population. The mean latent period between the ingestion of lye and development of carcinoma is 40 years. Patients with lye corrosion carcinoma of the esophagus tend to have a better prognosis than those with ordinary esophageal carcinoma. It is probably because the corrosion-induced scar tissue may restrict the early invasion of carcinoma. Here we reported two cases of esophageal carcinoma with past history of corrosive injury. Both patients had complications of pneumonia and empyema. The latent period between the occurrence of corrosive injury and the discovery of advanced esophageal carcinoma in Case 1 was three-and-a-half years only, far shorter than other reported cases.

並列關鍵字

lye corrosion esophagitis esophageal neoplasm

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