維生素E攝取與糖尿病患牙周狀況之相關性探討

The Relationship between Nutrient Intake and Periodontal Disease in Patients with Diabetes Mellitus

謝明家(Ming-Chia Hsieh) ； 許玉恒(Yu-Heng Hsu) ； 王貝婷(Pei-Ting Wang) ； 黃純德(Shun-Te Huang)

《Taiwan Journal of Oral Medicine Sciences》 25卷1期 (2009/04) Pp. 78-90

https://doi.org/10.7059/TJOMS.200904.0078

摘要

Background: Scientific evidence has reported severe periodontosis is a risk factor for poor glucemic control, and studies have shown that diabetes mellitus is the main reason for the worsening of periodontal disease. Nutrient intake may be one of the important factors affecting periodontal disease and diabetes mellitus; however, the relationship between nutrient intake, biochemical examination, and periodontal disease has rarely been discussed.
Objective: The objective of this investigation was to examine the relationship between nutrient intake and periodontal status in type 2 diabetes mellitus.
Material and Methods 211 patients with type 2 diabetes mellitus were recruited from the Department of Endocrinology in Kaohsiung Medical University Hospital from April to August, 2006. Periodontal status was evaluated by the Community Periodontal Index (CPI). Subjects were divided into two groups, according to CPI index; patients whose CPI≤2 is in the Periodontal-well-status group, and patients whose CPI≥3 is in the Periodontal-bad-status group. The nutritional intake status was evaluated by a 24-hour diet record.
Results: Distribution of subjeuts with A1C＞7.5% was significautly higher in CPI≥3 group than CPI≤2 group. The Periodontal-well-status group had higher vitamin E 5.8±33 mg/day (α-Tocopherol Equivalent; α-TE) intake compared with the CPI≥3 group 4.6±3.1mg/day (p=0.0329). Using multiple linear regression analysis to adjust for sex, age, education, body mass index and kilocalorie, Vitamin E intake was negativey related to CPI status (ß=-0.4, p=0.0410).
Conclusion: Periodontal status was related to long-term blood glucose control in diabetes patients. Upon adjustment for confounders, Vitamine E intake amount was related to periodontal status. Further study should be undertaken to examine the underlying mechanism.

關鍵字

牙周病 ； 糖尿病 ； 維生素E

並列摘要

Background: Scientific evidence has reported severe periodontosis is a risk factor for poor glucemic control, and studies have shown that diabetes mellitus is the main reason for the worsening of periodontal disease. Nutrient intake may be one of the important factors affecting periodontal disease and diabetes mellitus; however, the relationship between nutrient intake, biochemical examination, and periodontal disease has rarely been discussed.
Objective: The objective of this investigation was to examine the relationship between nutrient intake and periodontal status in type 2 diabetes mellitus.
Material and Methods 211 patients with type 2 diabetes mellitus were recruited from the Department of Endocrinology in Kaohsiung Medical University Hospital from April to August, 2006. Periodontal status was evaluated by the Community Periodontal Index (CPI). Subjects were divided into two groups, according to CPI index; patients whose CPI≤2 is in the Periodontal-well-status group, and patients whose CPI≥3 is in the Periodontal-bad-status group. The nutritional intake status was evaluated by a 24-hour diet record.
Results: Distribution of subjeuts with A1C＞7.5% was significautly higher in CPI≥3 group than CPI≤2 group. The Periodontal-well-status group had higher vitamin E 5.8±33 mg/day (α-Tocopherol Equivalent; α-TE) intake compared with the CPI≥3 group 4.6±3.1mg/day (p=0.0329). Using multiple linear regression analysis to adjust for sex, age, education, body mass index and kilocalorie, Vitamin E intake was negativey related to CPI status (ß=-0.4, p=0.0410).
Conclusion: Periodontal status was related to long-term blood glucose control in diabetes patients. Upon adjustment for confounders, Vitamine E intake amount was related to periodontal status. Further study should be undertaken to examine the underlying mechanism.

並列關鍵字

Periodontal disease ； Diabetes mellitus ； Vitamin E