Stroke is the one of the common neurological diseases. There are different types of strokes such as ischemic or hemorrhage strokes. Ischemic and hemorrhage strokes have different causes and effects in patients, both potentially leading patients disability or death. Most patients and caregivers have stress because of disabilities caused by strokes. The life change includes daily care, occupation, and economy. Stoke treatment in clinics focuses on medication and neurological surgery, often combined with rehabilitation or Chinese medication. In light of recent advances in stem cell therapy, with pre-clinical references and clinical trials, we can see future prospects for stem cell therapy in treating stokes.