以重複性穿顱磁刺激治療長新冠－案例分享

Treatment of Long COVID with Repetitive Transcranial Magnetic Stimulation:CaseReport

黃子容(Tzu-Jung Huang) ； 邱艶芬(Yann-Fen Chao) ； 尤世杰(Shih-Chieh Yu)

《秀傳醫學雜誌》 預刊文章 Pp. 1-19

https://doi.org/10.30185/SCMJ.202212/PP.0016

摘要

本篇報告我們提出了兩位因腦霧現象就醫接受重複性穿顱磁刺激（Repetitive transcranial magnetic stimulation, r-TMS）治療之案例，在2－4周間，根據FDA（Food and Drug Administration）protocol，治療處方：10HZ，3000 pulses/session，刺激強度:以患者測得之MT（motor threshold）值的70%開始，位置:F3- Left dorsal lateral posterior frontal cortex，on/off time: 4-second stimulation train，26-second inter-train interval，每次治療時間約為30－40分鐘，治療後產生顯著臨床改善效果，以蒙特利爾認知評估（Montreal Cognitive Assessment, MoCA），分數提升均大於3分以上，腦霧現象大幅改善，期許未來r-TMS應用於醫學上，能有效治療新冠肺炎產生之認知功能障礙。

關鍵字

長新冠 ； 腦霧 ； 輕度認知功能障礙 ； 重複性穿顱磁刺激

並列摘要

In this article, we describe two cases of patients with phenomena of brain fog receiving repetitive transcranial magnetic stimulation (r-TMS) treatment. According to the FDA (Food and Drug Administration)protocol within 2 - 4 weeks, the prescription are: 10HZ 3000 pulses/session, stimulation intensity: starting with 70% of the measured MT (motor threshold) value of the patient, location: F3-Left dorsal lateral posterior frontal cortex, on/off time: 4-seconds stimulation train , 26-seconds inter-train interval,each treatment period is about 30-40 minutes, This treatment yields an effect of significant clinical improvement after therapy. According to Montreal Cognitive Assessment(MoCA), the score was escalated by more than 3 points in both cases, and the brain fog phenomenon was greatly improved. It is expected that the application of r-TMS in medicine in the future can effectively treat the cognitive dysfunction caused by COVID-19.

並列關鍵字

Brain fog ； Long COVID ； Mild cognitive impairment(MCI) ； Repetitive transcranial magnetic stimulation(r-TMS)