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Neonatal Meningitis Caused by Coxsackievirus B5

克沙奇B5病毒所引起的新生兒腦膜炎

摘要


新生兒感染病毒時,通常比大小孩來的嚴重。而克沙奇B5病毒是最常造成嚴重疾病的病毒。在此,我們整理四個由克沙奇B5病毒引起的新生兒腦膜炎的臨床情形與大家分享。臨床上,他們都有發燒、食慾不振、以及活動力降低的情形。而兩個有嘔吐的症狀。腦脊髓液的分析報告:白血球的計數:340,495,580,660/公釐^3;紅血球的計數:0,36,125,250/公釐^3;葡萄糖值:47,52,55,59毫克/毫昇;總蛋白質:70,88,94,106毫克/毫昇。心臟與腦部超音波的檢查並無異狀,後業在病毒的分離培養報告出來則顯示:四個嬰兒都有在腦脊髓液裏培養出克沙奇B5病毒。之後他們都在沒有使用免疫球蛋白的情形下慢慢康復。出院之後,在六個月的回診追蹤裏,四個嬰兒都沒有發現任何的併發症。

並列摘要


Enteroviral infections are more severe in neonates than in older children, and coxsackievirus B is most frequently associated with severe neonatal disease. We summarize the course and clinical data of four neonates with meningitis caused by coxsackievirus B5. Their clinical symptoms and signs were persistent fever, poor appetite, and decreased activity, with vomiting in two. Laboratory analysis of cerebrospinal fluid revealed the following: white blood count, 340-660/mm3 red blood count, 0-250mm3 glucose level, 47-59mg/dl; and total protein level, 70-106mg/dl. Echocardiography showed normal heart function. Final bacterial cultures of the cerebrospinal fluid showed no growth, whereas viral cultures showed coxsackievirus B5. All patients recovered without intravenous immunoglobulin. No complications occurred at 6-month follow-up.

並列關鍵字

coxsackievirus B5 meningitis neonate

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