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心肌血流灌注SPET-CT衰減校正誤差-病例報告

Attenuation Correction Inaccuracy of Myocardial Perfusion SPET with CTAC-A Case Report

摘要


臨床所用之核醫心肌血流灌注斷層攝影(Myocardial Perfusion Single Photon Emission Computed Tomography; MP SPET)可搭配外部射源進行衰減校正(attenuation correction; AC),並藉由吻合位置校驗(position registration)的方式進行影像融合或是衰減校正,藉以減少因心臟本身結構、核醫藥物分佈等諸多因素造成的判讀誤差;本次案例即針對一例以Tc-99m MIBI進行MP SPET病例,因衰減校正誤差導致在SPET影像上造成前壁(Anterior wall)異常變暗(代表攝取或活性較低)經修正誤差後得到正確影像之案例提出討論。

並列摘要


In the examination of myocardial perfusion single photon emission computed tomography (MP SPET), using external radiation source like computed tomography (CT) has several advantages such as providing the attenuation correction factor (ACF) and image fusion(future, with Gated CT), which could avoid diagnosis errors by providing more accurate information of radio-pharmaceutical distribution and anatomical information of heart. However, misregistration would be a problem. This article discussed a clinical case of MP SPET with Tc-99m MIBI and showed the phenomena: how misregistration affected the result of MPSPET. The result showed the uniform decrease region on the anterior wall of heart, and also show the differences of image between proper and improper registration.

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