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左側乳房深吸氣閉氣切線放射治療準確性評估

Evaluation of Accuracy about Left Side Breast Deep Inspiratory Breath Hold (DIBH) Tangential Radiotherapy

摘要


左側乳房癌症病患接受放射治療時,使用即時位置管理系統的深吸氣閉氣切線治療方式搭配電子式影像裝置於治療前修正位移誤差,以提供準確的深吸氣閉氣切線治療。本研究共收集26位左側乳癌進行位移評估分析病患中,16位為深吸氣閉氣方式進行放射治療,10位為正常呼吸方式進行放射治療,在治療時利用電子式影像裝置循環連續擷取模式,擷取供評估分次與單次治療間位移所須影像。在治療準確上群體分次治療間的平均位移差異,深吸氣閉氣比正常呼吸下降0.76~2.16 mm,在系統誤差上比正常呼吸下降約0.36~0.79 mm,在隨機誤差上比正常呼吸下降約0.26~0.54 mm。對單次治療內而言,由於治療時閉住呼吸使的胸廓暫停移動,對整體位移差異除左右及前後方向系統誤差未有差異外,深吸氣閉氣皆比正常呼吸方式具有較少的位移差異。採行深吸氣閉氣方式進行乳房切線放射治療,使用電子式影像裝置作為治療前修正的依據,亦能達到與錐狀射束電腦斷層作為治療前修正依據的結果相同,因此採用該種治療方式具有一定的醫療價值。

並列摘要


Radiotherapy (RT) for breast cancer using deep inspiration breath hold (DIBH) technique and real time position manager (RPM) system has been adapted by many radiation oncology centers. In this study, we combined electronic portal imager system (EPID) to the procedure prior to each radiation treatment for the correction of setup errors. A total of 26 left side breast cancer females entered into this study. Sixteen acquired DIBH technique, while ten of them were irradiated on free breathing (FB). The inter-fraction and intra-fraction positional shifts were recorded using the EPID cine mode for continuous treatment images. After analyze, the inter-fraction setup error for DIBH was 0.76~2.16 mm less than FB, systemic error was less about 0.36~0.79 mm and random error was 0.26~0.54 mm less than FB. As for intra-fraction setup error, the DIBH have significant smaller positional shift exclude of systemic error at lateral and vertical directions under breath hold condition. In conclusion, EPID in combination with DIBH in breast cancer patients receiving RT yields a reliable correction power in daily setup.

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