還原蝦紅素對老化促進小鼠體內抗氧化狀態之影響

Effect of Astaxanthin on Antioxidative Statusin Senescence Accelerated Mice

王銘富(Ming-Fu Wang) ； 張巧幸(Chiao-Hsing Chang) ； 林芳儀(Fang-Yi Lin) ； 吳青蓮(Ching-Lein Wu)

《美容科技學刊》 1卷1期 (2002/12) Pp. 39-54

https://doi.org/10.30001/JIES.200212.0004

摘要

Astaxanthin of antioxidative ability was stronger than f3-carotene. The purpose of this study was to examine the effect of astaxanthin supplement on antioxidative status in senescence accelerated mice (SAMP8). Six-month-old male mice were divided into three groups: casein diet group (control group) and casein diet supplemented with 0.01%, 0.025% Astaxanthin. After 16 weeks feeding, body weight and food intake were performed during the experiment. The superoxide dismutase (SOD) activity of liver and brain were analyzed after sacrificed. The results showed that body weight and food intake were no significantly among three groups. The SOD activity of liver in the 0.025% Astaxanthin group was higher than control group (P＜0.05). The SOD activity of brain was no significantly among three groups, but in the 0.025% Astaxanthin group was higher than 0.0 1% Astaxanthin and control group. In summary, we conclude the supply of Astaxanthin may improve antioxidative system on liver and brain in SAMP8 mice.

關鍵字

還原蝦紅素 ； 抗氧化 ； 老化促進小鼠

並列摘要

Astaxanthin of antioxidative ability was stronger than f3-carotene. The purpose of this study was to examine the effect of astaxanthin supplement on antioxidative status in senescence accelerated mice (SAMP8). Six-month-old male mice were divided into three groups: casein diet group (control group) and casein diet supplemented with 0.01%, 0.025% Astaxanthin. After 16 weeks feeding, body weight and food intake were performed during the experiment. The superoxide dismutase (SOD) activity of liver and brain were analyzed after sacrificed. The results showed that body weight and food intake were no significantly among three groups. The SOD activity of liver in the 0.025% Astaxanthin group was higher than control group (P＜0.05). The SOD activity of brain was no significantly among three groups, but in the 0.025% Astaxanthin group was higher than 0.0 1% Astaxanthin and control group. In summary, we conclude the supply of Astaxanthin may improve antioxidative system on liver and brain in SAMP8 mice.

並列關鍵字

astaxanthin ； antioxidation ； senescence accelerated mice SAMP8 To whom correspondence should be addressed

參考文獻

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