This paper describes the planning and implementation of the objective structured clinical examination (OSCE) for postgraduate year (PGY) pharmacists in teaching hospitals of different levels of in eastern Taiwan. The purpose of OSCE was to evaluate the training outcomes of PGY pharmacists and the experiences can form a solid foundation for similar evaluation programs in the future. This joint OSCE was conducted from 2013 to 2014, with PGY 1 and 2 junior pharmacist participants from six teaching hospitals in three different counties in eastern Taiwan. The OSCE examiners, with assistance from standardized patients in simulating clinical scenes, could observe the professional skills of the junior pharmacists including consultation of correct drug usage, health education of drug side effects, clarifying and resolving patients' questions, and the ability to communicate with patients and physicians. In the meantime, the joint OSCE could help indicate the places to be improved, apprehend the professional ability of the newly employed pharmacists and enhance patient safety.