Fibrodyplasia ossificans progressive (FOP) is a rare disease caused by autosomal dominant disorder. It is characterized by congenital malformations of the great toes and progressive heterotopic endochondral ossification (HEO) that cause cumulative immobility. During the 1st decade of life, most children with FOP develop episodic inflammatory soft tissue swelling and later develop into ossification at injury site in response to soft tissue trauma and muscle damage. Special medical and dental consideration are needed to prevent injury or iatrogenic harm. Herein we report on the dental considerations and managements of a case of three-year-old case with fibrodysplasia ossificans progressiva.