In this paper was to explore the effectiveness on the mathematical problem solvingafter the using meta-cognitive strategies for students with learning disabilities by case analysis. It’s supported by practical cases as evidence and instructions. And some discussions included the background of the study, the influencing factors of the students' problem solving, the theoretical basis, the teaching principles of the meta-cognitive strategies, and the practical sharing of the meta-cognitive strategies after the application of the mathematics problem solving. Finally, researchers listed some conclusions and recommendations.