Interprofessional collaboration in research has been supported in the health field. With the recognition that action research (AR) is increasingly viewed as a crucial research tool in health, this paper focuses on collaboration in the interprofessional action research process. It is believed that the collaborative process of interprofessional inquiry in health AR groups can help increase the quality of research outcomes and then efficiently improve problems in health care practice. While the strength of interprofessional collaboration for AR in health settings contributes to a wide variety of professional perspectives, its potential weakness ironically comes from such advantage for producing wider knowledge in solving health problems. To facilitate the collaborative process in AR for interprofessional inquiry and knowledge is challenging due to professional differences which affect the research group dynamics. Interprofessional socialization has been identified as one solution to the difficulties with the collaborating group. In addition, it is argued that collaborative approach must also be inquiring, reflective and active through the entire AR process.