Central venous catheter (CVC) insertion is a common procedure in major operations and functions to provide fluid access and a parameter in hemodynamic monitoring. However, CVC insertion is risky, resulting in complications, such as arterial injury, stroke, and hematomas. Here we reveal a case on an incident that occurred during CVC insertion. The catheter misplacement resulted in the extravasation of the right common carotid artery. For this case, we concluded that surgical management would be the most effective to safely treat arterial puncture during jugular vein catheterization.