Chronic Myelomonocytic Leukemia with Hypereosinophilia in a Patient

慢性髓性白血病以高嗜伊紅性血症表現之病例報告

蔡孟軒(Meng-Hsuan Tsai)

《童綜合醫學雜誌》 15卷S期 (2021/09) Pp. 67-70

https://doi.org/10.3966/20713592202109150S010

摘要

Hypereosinophilia (HE) is defined as an absolute eosinophil count ＞ 1.5 × 10^9/L (or ＞1500 cells/μL) in the peripheral blood. Hypereosinophilia may be caused by events like allergic reactions, parasitic infections, drug reactions, paraneoplastic syndromes, and endocrine problems. In some cases, HE could be idiopathic and has limited clinical significance or is just secondary to other tissue damage like hypereosinophilic syndrome. However, hematological malignancies must be considered. We present a case with fever and hypereosinophilia that was eventually diagnosed as chronic myelomonocytic leukemia.

關鍵字

eosinophil ； hypereosinophilia ； chronic myelomonocytic leukemia

並列摘要

高嗜伊紅性血症是一少見的血液疾患，主要表現是周邊血液或是組織間的嗜伊紅性血球細胞增加。其定義為絕對嗜伊紅性血球大於1.5 x 109/L（或血液中嗜伊紅性血球＞1500細胞／毫升）。高嗜伊紅性血球症可能會因過敏反應、寄生蟲感染、藥物刺激、腫瘤伴生神經症候群以及內分泌失調等因素相關，在某些患者身上，高嗜伊紅性血球症可為原發性，表現為無任何臨床症狀，亦可伴有其他組織器官因嗜伊紅性血球侵犯所產生的損害，此時稱為高嗜伊紅性血症；此外血液方面的惡性腫瘤也必須列入考量。在此我們探討一位伴有發燒及高嗜伊紅性血球症的患者，之後診斷出是慢性髓性單球性白血病。

並列關鍵字

嗜伊紅性球 ； 高嗜伊紅性血症 ； 慢性髓性白血病