- 期刊
- OpenAccess
Effect of Dietary Carbohydrate Restriction on an Obesity-Related ＂Prevotella＂-Dominated Human Fecal Microbiota
並列摘要
Relatively few studies have been conducted on the effect of diet on the intestinal microbiota. We followed the response of the fecal microbiota to a carbohydrate-restricted diet in an obese volunteer. The community composition was estimated through 16S rRNA gene sequence analysis. Bacteria of the ＂Prevotella＂ genus dominated the microbiota. Elimination of carbohydrates from diet triggered an immediate decrease in ＂Prevotella＂, compensated by the increase in all other bacteria, and higher fluctuations in the community composition. Fecal microbiota changed back to its previous structure no later than 4 weeks after reintroducing carbohydrates in diet. Our results show the dependence of ＂Prevotella＂ on dietary carbohydrates and confirm the resilience of the microbiota to short-term dietary interventions. The potential link between ＂Prevotella＂ and obesity warrants further research.
延伸閱讀
- Yu, J., Marsh, S., Hu, J., Feng, W., & Wu, C. (2016). The Pathogenesis of Nonalcoholic Fatty Liver Disease: Interplay between Diet, Gut Microbiota, and Genetic Background. Gastroenterology Research and Practice, 2016(), 467-479-062. https://doi.org/10.1155/2016/2862173
- Puddu, A., Sanguineti, R., Montecucco, F., & Viviani, G. L. (2014). Evidence for the Gut Microbiota Short-Chain Fatty Acids as Key Pathophysiological Molecules Improving Diabetes. Mediators of Inflammation, (2014-1), 316-324. https://doi.org/10.1155/2014/162021
- 楊佳芳（2023）。Effects of pterostilbene and its derivative 3'-hydroxypterostilbene on intestinal inflammation and dysbiosis in obesity mice induced by high-fat diet using fecal microbiota transplantation〔碩士論文，國立屏東科技大學〕。華藝線上圖書館。https://doi.org/10.6346/NPUST202300088
- 張芷婷（2019）。Investigation into the effects of dietary emulsifiers on gut microbiota, mucus layer and metabolism〔碩士論文，國立臺灣大學〕。華藝線上圖書館。https://doi.org/10.6342/NTU201903876
- Golab, A. Z., Kocelak, P., Aptekorz, M., Zientara, M., Juszczyk, L., Martirosian, G., Chudek, J., & Glinianowicz, M. O. (2013). Gut Microbiota, Microinflammation, Metabolic Profile, and Zonulin Concentration in Obese and Normal Weight Subjects. International Journal of Endocrinology, 2013(), 346-354-139. https://doi.org/10.1155/2013/674106