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Experimental Assessment of Radiation Detectors for the Detection Efficiency Using F-18 Labeled Radiopharmaceuticals

利用不同活度F-18 FDG比較輻射偵檢器在不同距離之下的偵測效率

摘要


Background: To detect the radioactive contamination is important for working in a nuclear medicine department not only to prevent and control the contamination of radionuclides but also to ensure the safety of patients and medical staff. Selecting a reliable and suitable radiation detector remains a disturbing issue. In the current study, an experimental method of choosing the optimal radiation detector was described, based on their detection efficiency. Methods: Five available radiation detectors were used in this study, including three area detectors (AL375, AT1121, and ARM-LD) and two personal detectors (Dosiman and MiniRadiac). Using F-18 FDG as a radioactive source mimicking the radioactive contamination, the effective dose rate of each detector was measured at predetermined distances. The linear regressions of each detector for the effective dose rate and the inverse square of the distance were calculated, and the correlation coefficients of each linear regression were determined. Results: The correlation coefficient was average above 0.9000 in all five radiation detectors. For the two personal detectors, MiniRadiac showed better detection efficiency. Among the area detectors, the detection efficiency of AT1121 was the best and the most sensitive detector compared to the other four. Conclusion: The radiation detectors used in this study showed similar but distinguished detection efficiency, indicating that this experimental method was suitable for choosing an optimal radiation detector to facilitate the detection and prevention of radioactive contamination. As for the surveillance of patients and visitors with unexpected radioactive contamination in the hospital, such as the emergency department, our experience described here may provide an easy and convenient model for establishing the rapid response to manage the radioactive contamination.

並列摘要


目的:在核子醫學的領域中,如何預防輻射的曝露是被注意的課題,因此如何及時有效的偵測到輻射是很重要的。本研究希望透過比較各偵檢器在不同距離和不同活度下所量測之伽瑪輻射劑量率的線性關係,找出較適用於醫療院所工作人員及場所所使用的輻射偵檢器。方法:在此研究當中,選用了五種不同型態的偵檢器。分別是三種區域偵檢器:Ludlum Model 375、Radiation dosimeter AT1121和ARM-LD及兩種個人偵檢器:MiniRadiac和Dosiman。在固定距離下(30,45,60,75,90,105,120,135,150,165,180,195公分),以各偵檢器去偵測不同活度的氟-18氧化去氧葡萄糖(2mCi、1.5mCi、1mCi、0.8mCi、0.5mCi、0.2mCi和0.1mCi)。利用線性迴歸,分析各偵檢器所測得的劑量率與距離平方反比。結果:分析各迴歸係數後,五種偵檢器的平均偵測效率均大於90%。在區域偵檢器方面,以AT1121的偵測效率最佳;個人偵檢器,則以MiniRadiac的偵測效率較佳。結論:本研究中使用的輻射偵檢器,偵測效率雖然相近,但是在統計上仍有明顯的差異。闡明本研究中的實驗方法,確實適合用於鑑別不同輻射偵檢器對於放射性污染的偵測效率。本研究提供了一個簡單方便的實驗模組,以利做為預防輻射曝露與防護放射性污染。

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