超臨界二氧化碳萃取木香精油及其成份分析之研究

Supercritical Carbon Supercritical Carbon of Saussurear Radix and Analyzing Its Composition

潘懷宗(Wynn HT Pan) ； 謝秉甫(Bing-Fu Hsieh) ； 張光雄(Kuang-Hslung Chang) ； 杜高閔(Gau-Min Duh)

《化學》 53卷2期 (1995/06) Pp. 155-162

https://doi.org/10.6623/chem.1995014

摘要

利用超臨界二氫化碳萃取(SFE-CO_2)來進行木香藥材的精油萃取，並針對四種不同的壓力及溫度，來評估精油產率的高低。同時，使用氣相層析儀來分析木香精油中兩種主要有效物質(木香烯內酯及去氫木香內酯)的含量。結果顯示，當萃取壓力在3500 psi，溫度在50℃時，SFE-CO_2 對木香烯內酯有最大之萃取能力。另一方面，當萃取壓力在1500 psi，溫度在35℃時，SFE-CO_2對去氫木香內酯有最大之萃取能力。本文針對某一特定有效物質進行萃取，是SFE-CO_2萃取有效化合物的應用實例，值得各界先進參考與利用。

關鍵字

木香烯內酯 ； 去氫木香內酯 ； 氣相層析儀

並列摘要

By using a supercritical carbon dioxide extraction (SFE-CO_2) technique, we extracted essential oils from Saussureae Radix. Four different extraction conditions were used in this Study: (1) 1500 psi, 35 °C; (2) 3500 psi, 35 °C; (3) 1500 psi, 50 °C and (4) 1500 psi, 50 °C. The highest yield of essential oils was found at the condition of 3500 psi. 50 °C and a comparable yield was else obtained at 3500 psi/35 °C. By using a gas chromatography/ frame ionization detector, we then quantified the content of constunolide and dehydrocostuslactore, (two major active components) in the essential oil under four differnet conditions. Results tell us that at 35 °C/ 3500 psi, the quantity of costunolide in the extracted oil was the highest, and at 35 °C/1500 psi, the dehydrocostuslactone could be extracted by SFE-CO_2 must efficiently. Since no experienced formula is good enough to predict the extraction efficiency of compounds, the results in this study were useful for the data bank of SFE-CO_2 extraction.

並列關鍵字

Costunolide ； Dehydrocostuslactone ； Gas chromatography