The electrochemistry experiment plays an important role in chemistry course. However, environmental and safety considerations arise. This article introduces designs and operations of microscale electrochemistry experiment in both microscale environmental electrolysis and microscale hydrogen / oxygen fuel cells. The results indicate that the microscale method in electrochemistry can eliminate the above-mentioned problems. With this new simple apparatus, the amounts of chemicals consumed and waste produced during these microscale electrochemistry experiments were greatly reduced in comparison with those in the traditional electrochemistry experiments. Hence, the promotion of microscale electrochemistry experiment apparatus for chemistry course may be worthy.