- 期刊
毛筆尖電噴灑質譜法的開發與應用
Development and Application of a Brush-Spray/Mass Spectrometry by a Writing Brush
摘要
本研究基於紙片電噴灑之相似原理，成功開發了毛筆尖電噴灑質譜法。利用這方法，分析樣品可以用毛筆採集後，配合質譜儀進行離子的偵測。連接毛筆的溶劑卡匣是以ABS樹脂為材料，用3D列印機列印而成的。卡匣內有溶劑可以使筆毛保持濕潤，不僅可以進行非破壞性樣品採集，當卡匣另一端接上高壓電源時，還可以直接進行離子化。實驗結果發現，以大滅松為測試樣品，偵測極限可達0.1 ppm。由於毛筆柔軟且具有吸水性，即使是蔬菜表面上殘留農藥大滅松也可以成功採集並且偵測到。本文將介紹毛筆尖電噴灑質譜法的應用，毛筆溶劑卡匣的製作方法、筆毛種類的偵測結果的影響、及最佳化實驗條件等也一併報告。
並列摘要
Using a small writing brush and analogous to paper-spray mass spectrometry, the analytes can be collected, evaporated and then ionized. ABS (acrylonitrile butadiene styrene) was used as the starting material and the body of the solvent-cartridge was produced by means of a commercial 3D-printer. The writing brush was embedded inside a 3D-printed cartridge, in which a solvent was supplied to rinse the brush. The writing brush-cartridge is disposable and it has various functions, including non-invasive sampling, sample-evaporation and ionization. As a result, when a type of pesticide was selected as the test sample (dimethoate; C5H12NO3PS2), the limit of detection was determined to be 0.1 ppm. Collecting the pesticide from a leaf-surface (lettuce) was also successful. The process for fabricating the writing brush-cartridge and the optimized experimental conditions are reported herein.
延伸閱讀
- 莊育傑（2004）。毛細管電層析/電灑法質譜儀之開發與應用〔碩士論文，國立臺灣大學〕。華藝線上圖書館。https://doi.org/10.6342/NTU.2004.01713
- 劉人瑛（2016）。3D列印容槽鑲嵌毛筆尖電噴灑/質譜法的開發與研究〔碩士論文，國立臺灣師範大學〕。華藝線上圖書館。https://doi.org/10.6345/NTNU202204581
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