This is a case report of myocardial perfusion imaging on dextrocardia patient with single ventricle. It is rare of myocardial perfusion imaging for dextrocardia patient. By modifying the SPECT scanning angle could solve this situation. We set the scan starting angle at RPO 45° and ending angle at LAO 45° for this case. Because of dextrocardia patient with single ventricle possess potential risk of myocardial ischemia, ventricular hypertrophy and heart failure. Therefore close monitoring vital sign is necessary when Dipyridamol be injected. We address this case report to the same trade for commenting.