靜電紡絲輔助生物列印技術

Progress in Electrospinning Assisted Bioprinting Technology

林央正 ； 李昌周 ； 王登彥 ； 林東穎

《機械工業雜誌》 455期 (2021/02) Pp. 61-69

摘要

本文介紹靜電紡絲技術應用於生醫領域上，可將高分子材料列印至更微小化線寬，並介紹目前開發可列印網格狀圖案或圓形圖案的靜電紡絲輔助生物列印機。藉由同軸靜電紡絲技術可列印出具有包覆性芯鞘形高分子線條。以PVA材料在實驗設備上進行近場電紡，能夠列印出線寬落在數十至數百μm尺度範圍，並且具有包覆功能之細微線條，可藉此研究突破傳統積層造最小線寬的限制，擴大積層製造的應用領域。

關鍵字

靜電紡絲 ； 積層製造 ； 生物列印 ； 支架

並列摘要

This article describes development of electrospinning technology to achieve finer diameter printing with polymer materials. The current developed electrospinning-assisted bioprinter with capability of printing grids and circular patterns will be introduced. This bioprinter can print core-sheath polymer lines by using the coaxial electrospinning technique. PVA or PLA material was used in our laboratory electrospinning equipment to obtain core-sheath line widths within the range of tens to hundredsμm. Through this research, we have demonstrated to overcome the width limitation of the conventional additive manufacturing and expand its applications.

並列關鍵字

Electrospinning ； Additive manufacturing ； Bioprinting ； Scaffold

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