With the development of Intelligent Manufacturing, Smart Machinery becomes a major trend. However, the method of simply attaching the Smart Machine Box to the machine has its limitations. In the future, at the beginning of machine design, intelligence must be incorporated into the design specifications to produce native intelligent machinery. Smart Machinery and Intelligent Manufacturing will cooperate to create greater value. The key technology lies in the deep integration of IT and OT. With the development of comprehensive data integration and innovative applications, the improvement of industrial mechanisms, mathematical models and management mechanisms, the manufacturing industry can rapidly respond to internal and external changes. Thus, companies can always stay optimized at the moment.