The current study conducted an empirical study to explore the effects of internal marketing, relationship quality and salary welfare on resignation tendency. Besides, the moderating effects of salary welfare were investigated. The results indicated that both corporate internal marketing mechanisms and employee's relationship quality could significantly affect employee's resignation tendency, while training and empower had the most significant effect on resignation tendency. Besides, the degree of satisfaction on salary welfare had significant negative influence on employee's resignation tendency, while the effect of trust and commitment was most significant. Moreover, the degree of satisfaction on salary welfare could moderate the effects of internal marketing and relationship quality on employee's resignation tendency significantly.