The research on the mechanical characteristics of concrete filled steel tubular composite frame under high temperature fire environment is one of the research hotspots. In this paper, The simulation results of the deformation and displacement of the single‐layer single span and two‐layer two‐span composite frame structure are deeply studied, including the different temperature field, structural field, structural field of each beam and column The results show that: the flexure effect of mode 1 is larger than that of condition 2, which indicates that the flexural effect of two‐story two span CFST composite frame under full cross‐section fire is larger than that of condition 2 It should be better. The research results can provide reference value for the reinforcement and repair of CFST composite frame under high temperature fire.