- 期刊
- OpenAccess
Autophagy Therapeutic Potential of Garlic in Human Cancer Therapy
摘要
Cancer is one of the deadliest diseases against humans. To tackle this menace, humans have developed several high-technology therapies, such as chemotherapy, tomotherapy, targeted therapy, and antibody therapy. However, all these therapies have their own adverse side effects. Therefore, recent years have seen increased attention being given to the natural food for complementary therapy, which have less side effects. Garlic (大蒜 Dà Suàn; Allium sativum), is one of most powerful food used in many of the civilizations for both culinary and medicinal purpose. In general, these foods induce cancer cell death by apoptosis, autophagy, or necrosis. Studies have discussed how natural food factors regulate cell survival or death by autophagy in cancer cells. From many literature reviews, garlic could not only induce apoptosis but also autophagy in cancer cells. Autophagy, which is called type-II programmed cell death, provides new strategy in cancer therapy. In conclusion, we wish that garlic could be the pioneer food of complementary therapy in clinical cancer treatment and increase the life quality of cancer patients.
延伸閱讀
- Meng, C. L., Shyu, K. W., & Chang, P. (1989). The Inhibitory Efficacy of Garlic Fractions on the Experimental Oral Cancer of Hamster. Journal of Medical Sciences, 10(3), 131-140. https://www.airitilibrary.com/Article/Detail?DocID=10114564-198906-201308020005-201308020005-131-140
- Cocom, L. M. (2022). The Assessments on Antimicrobial, Antioxidant, and Anticancer Activity of Raw, Fermented, and Aged Garlic [master's thesis, National Pingtung University of Science and Technology]. Airiti Library. https://doi.org/10.6346/NPUST202200326
- Xiao, J. (2012). Protective mechanisms of garlic and wolfberry derivatives on acute andchronic liver injury animal models [doctoral dissertation, The University of Hong Kong]. Airiti Library. https://www.airitilibrary.com/Article/Detail?DocID=U0029-0511201300009001
- 劉佳玲、朱妝音（2017）。Evaluation and Preparation of Antimicrobial Particles from Aqueous Garlic Extract。臺灣農業化學與食品科學，55(1)，41-48。https://doi.org/10.6578/TJACFS.2017.004
- 汪曉琪（2010）。Anticancer activity and its molecular mechanisms of allyl sulfides of garlic essential oil in human skin cancer cells〔博士論文，國立臺灣大學〕。華藝線上圖書館。https://doi.org/10.6342/NTU.2010.01841