At present, students are weak in actual drawing and cannot independently draw standard engineering drawing in the teaching of mechanical drawing course in higher vocational colleges, in allusion to these problem, under the guidance of OBE idea, informatization teaching mode of mechanical drawing course in higher vocational college based on project course is put forward, taking the part drawing chapter as an example, the specific reform measures of the course structure, course contents, teaching organization ways, evaluation system and the construction framework of information teaching platform were explained, the analysis of teaching effect was carried out, moreover, compared to the effect of traditional teaching practice, the effectiveness and actual value of this teaching method were verified, which provides reference for teaching reform of other courses.