This work is based on a novel structure of transmission line — slotted semi-coaxial line and adopts the proposed peripheral circuits to solve the problem of global interconnect. This work adopted TSMC 0.18μm technology and it is proved by the measurement results that the proposed structure can transmit up to 4 Gbps data at 1.8V peak-to-peak. The system which adopted the proposed transmission line is also faster than the conventional RC repeater.