In this thesis, we study the quality improvement of fastener wires in the spheroidization process of using the roller hearth short time cycle annealing furnace (STC). First, we screen key factors and decide their levels through using statistical methods. Then, the fractional factorial design method is used to determine the optimal model. The optimal treatment is searched by using response surface methods. The performance of the obtained optimal treatment was compared with the existing treatment for production. We find that the proposed optimal treatment can reach a significant improvement for the quality of fastener wires, and the yield of fastener wire products is successfully enhanced based on using the proposed optimal treatment than using the exiting treatment.