可分解性磁性生醫玻璃之備製及研究

The Study and Fabrication of Biodegradable Magnetic Bioglass

呂世旗(Shih-Chi Liu)

指導教授 ： 許淙慶 ； 林峰輝

國立臺北科技大學/工程學院/材料及資源工程系所/碩士(2006年)

摘要

本研究主要是將Na2O-CaO-SiO2-P2O5系生醫玻璃,添加15、30、50wt%氧化鐵(Fe2O3),以煆燒的方式將Na2O、CaO、SiO2、P2O5粉末混合氧化鐵粉末在高溫(1400℃)煆燒後淬火,使之形成含磁性之生醫玻璃材料,並探討磁性生醫玻璃在不同含鐵量下的磁性變化,且利用交流電螺旋磁場使其發生磁滯損失之情形,藉以觀察生醫玻璃溫度之變化。
Na2O-CaO-SiO2-P2O5系生醫玻璃具有生物可降解性,生物相容性,置於生物體內會被免疫系統所規避,又因此生醫玻璃含有氧化鐵,具有磁性,故可在一外加磁場作用下,使生醫玻璃產生溫度,進而以溫熱療法方式治療腫瘤細胞,也可用於當做藥物載體,藉著溫度的控制,釋放藥物以進行治療。

關鍵字

生醫玻璃 ； 生物可降解性 ； 磁滯損失 ； 溫熱療法

並列摘要

This research is mainly to Na2O-CaO-SiO2-P2O5 series bio-glass, add 15 , 30, iron oxide of 50wt% (Fe2O3 ), mix Na2O , CaO , SiO2 , P2O5 powder the iron oxide powder by way of burning, in quench after sintering of high temperature (1400℃), make its forming include the bioglass material of magnetic, and probe into the magnetic bioglass magnetic change under different iron content, and utilize the spiral magnetic field of alternating current to enable its the situation of hysteresis loss take placing , use to observe the change of bioglass temperature.

The Na2O-CaO-SiO2-P2O5 series bioglass has biodegradable, biocompatible, will be evaded to put by the immune system, bio-glass contains the iron oxide , have magnetic, so can be under one and magnetic field function, make bioglass produce temperature, and then treat the tumour cell by way of hyperthermia, and can be used for regarding as Drug carriers, release medicines making use of the control of temperature in order to treat.

並列關鍵字

bioglass ； biodegradable ； hysteresis loss ； hyperthermia

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