新型生醫用陶瓷之生物相容性之研究

Research of biocompatibility on the novel medical-grade bioceramics

蔡東螢(Dong-Ying Tsai)

指導教授 ： 黃瓊芳

臺北醫學大學/口腔醫學院/牙醫學系碩博士班/碩士(2013年)

摘要

無資料

關鍵字

抗菌生醫陶瓷 ； 氧化釔穩定氧化鋯 ； 銀

並列摘要

This study investigates the microstructure and mechanical properties of novel antimicrobial bioceramics composited with various fractions of Ag/yttria-stabilized zirconia (YSZ) and sintered at different temperatures. X-ray diffraction patterns of all the composites show a single crystalline phase of tetragonal YSZ regardless of Ag content. However, the grain size enlarges with increased sintering temperature. The composite sample containing 0.5 wt% Ag and sintered at 1400 °C for 1 h possesses a maximum grain size of approximately 0.3 μm. At high sintering temperature, the micro-hardness increases because of the reduction of porosity. From the MTT assay, time-dependent proliferation shows that the Ag/YSZ composite ceramic is not cytotoxic. Thus, the Ag/YSZ composite ceramic possesses good biological activity, useful for its applications in biomedicine and dentistry.

並列關鍵字

antimicrobial bioceramics ； yttria-stabilized zirconia ； Ag

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