臺灣成年人飲食型態與發炎指標之相關性

The correlations between dietary patterns and inflammatory markers among adults in Taiwan

蔡佩玲(Pei-Ling Tsai)

指導教授 ： 趙振瑞

共同指導教授 ： 徐建業(Chien-Yeh Hsu)

臺北醫學大學/公共衛生暨營養學院/保健營養學研究所/碩士(2014年)

https://doi.org/10.6831/TMU.2014.00094

摘要

有鑑於過去研究指出飲食中所包含之成分對於發炎反應具有影響力，且由於慢性發炎與許多慢性疾病具有相關性，因此本研究欲探討國人飲食型態與發炎指標之相關性。本研究使用美兆健康管理機構已建置完成之資料庫包含482,641位參與者之資料，篩選介於20到65歲之成年人，並排除曾罹患癌症或心血管疾病者及資料不完全者，共有145,695分資料進行分析，將參與者之飲食型態分為五大類分別為動物性蛋白質、主食、蔬菜與水果、油脂及精製糖飲食型態，以統計軟體SAS 9.3版分析飲食型態與發炎反應指標白血球、嗜酸性白血球、嗜中性白血球、嗜鹼性白血球、淋巴球、單核球、C反應蛋白、甲型胎兒蛋白及癌胚抗原濃度之相關性。結果顯示經年齡、身體質量指數、腰臀比、職業、教育程度、婚姻狀況、抽菸、喝酒、吃檳榔程度及運動習慣之校正後，攝取較多動物性蛋白質、油脂及精製糖之飲食型態顯著增加白血球濃度，攝取較多蔬菜與水果之飲食型態顯著減少白血球濃度，但男女性參與者攝取較多精製糖之飲食型態皆顯著與C反應蛋白濃度呈負相關，此外男女性參與者之飲食型態攝取在本研究中對其他發炎指標未有一致性之結果，顯示飲食對於發炎指標之影響可能具有男女差異。

關鍵字

飲食型態 ； 發炎反應 ； 白血球 ； C反應蛋白

並列摘要

Dietary components have been associatied with inflammatory response, and chronic inflammation may influence development of chronic diseases. The aim of this study was to investigate the associations between dietary patterns and inflammatory markers of adults in Taiwan. Database were obtained from MJ health management institution, and included 482,641 participants. The participants aged between 20 to 65 years old without history of cardiovascular disease and cancer were selected. After exclusion of missing data, a total of 145,695 participants were remained for analysis. According to dietary patterns, participants were categorised into five group: animal protein, cereal, vegetable and fruit, oil and sugar dietary pattern. Statistical analysis was used SAS version 9.3. The correlations between dietary patterns and inflammatory markers including white blood cells, eosinophils, neutrophils, basophils, lymphocytes, monocytes, C reactive protein, alpha-fetoprotein and carcinoembryonic antigen were analyzed. After adjusted for age, body mass index, waist hip ratio, occupation, education, marriage, smoking status, drinking habits, betel nuts chewing and exercise habits, the intake of animal protein, oil and sugar dietary pattern was positively associated with white blood cell concentrations, and the intake of vegetable and fruit dietary pattern was negatively associated with white blood cell concentrations in both genders. However the intake of sugar dietary pattern intake was negatively correlated with C reactive protein concentrations in both genders. Furthermore, the correlations between dietary patterns and other inflammatory markers were different in males and females.

並列關鍵字

dietary pattern ； inflammatory response ； white blood cells ； C reactive protein

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