The applications of frequency synthesizer, which plays a big role, are widely used in the wireless communication. The more wireless communication is booming up, the more important synthesizer is. Nowadays, the most of designer focus on radio frequency component of working at low-voltage operation to extend the time of stand by. In this thesis, a voltage control oscillator is designed for the use in a frequency synthesizer worked at low voltage. Besides, a loop filter is also designed to fit the specifications of the frequency synthesizer. Finally, the frequency synthesizer is developed and its characteristic parameters are also measured. From the measured data, it is shown that the developed frequency synthesizer has a good operation function.