- 學位論文
以脈波傳導特徵評估周邊動脈血管之生理訊息研究
Physiological Signal Analysis of Peripheral Arteries by Pulse Wave Characteristics
摘要
心率變異可用來觀測人的自律神經活性，隨著穿戴式裝置技術的發展，使得光體積脈波訊號常被用來量測脈率，進而分析脈率變異後，亦同時被取代為心率變異。然而，心率會受到呼吸深淺及快慢的影響，而造成不同位置量測的心率變異與脈率變異有所誤差。 本研究依據呼吸性竇性心律不整(RSA)的特性，控制呼吸之節率與潮量，探討心電訊號與光體積脈搏訊號之變異量，進而評估周邊動脈血管之特性。本實驗使用多項生理監測系統，在坐姿狀態同時量測呼吸率、心電訊號及四肢的光體積變化訊號，分析正常心率間的標準誤差量(SDNN)。 實驗結果發現正常年輕族群在控制不同呼吸之節率與潮量，心率變異與脈率變異有顯著差異(P值 < 0.05)，在四肢之脈率變異則無顯著差異；以年齡來分析，年輕族群在脈波傳遞時間(PTT)上可看上肢與下肢有顯著差異，但年長者則無。因此，由實驗結果顯示在呼吸期間之脈率變異與心率變異有所差異。
並列摘要
Heart rate variability (HRV) can be applied to observe the autonomic nervous system activity of human beings. With the development of wearable device technology, the PPG signal is often applied to measure pulse rate and furthermore to analyze the pulse rate variability (PRV), considered to be equivalent to HRV. However, the heart rate is affected by depth and speed of breath that causes different results when HRV and PRV are measured on different locations. Based on the characteristics of the respiratory sinus arrthymia (RSA), the beat rate and tide volume of breath were controlled and the variability of PPG and ECG signals were discussed; furthermore, the characteristics of peripheral arteries were evaluated. Several PSG applied were respiration rate measured with sitting position, and ECG signals and PPG variability of four limbs to analyze the SDNN of normal to normal beat. It was found that obvious difference ( p <0.05) shown between HRV and PRV when normal young groups were controlling different beat rate and tide volume; however, no obvious ones shown on the PRV of four limbs. To analyze based on age, obvious difference between upper limbs and lower ones was shown on the PTT of young group instead of the elderly. Therefore, the result showed there are difference between PRV and HRV during breath.